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Exponentiated confidence interval for an average of log-transformed parameters

Source: R/meta_ave.R
meta.ave.gen.log.Rd

Computes the estimate, standard error, and confidence interval for an average of any type of log-transformed parameter (e.g., log mean ratio, log proportion ratio, log odds ratio) from two or more studies.

Usage

meta.ave.gen.log(alpha, est, se, bystudy = TRUE)

Arguments

alpha

alpha level for 1-alpha confidence

est

vector of log-transformed parameter estimates

se

vector of standard errors for log-transformed estimates

bystudy

logical to also return each study estimate (TRUE) or not

Value

Returns a matrix. The first row is the average estimate across all studies. If bystudy is TRUE, there is 1 additional row for each study. The matrix has the following columns:

  • Estimate - estimated log effect size (from input)

  • SE - standard error of log effect size (from input)

  • LL - lower limit of the confidence interval

  • UL - upper limit of the confidence interval

  • exp(Estimate) - exponentiated estimate

  • LL - lower limit of the exponentiated confidence interval

  • UL - upper limit of the exponentiated confidence interval

Examples


est <- c(.165, .193, .218)
se <- c(.0684, .0921, .0882)
meta.ave.gen.log(.05, est, se, bystudy = TRUE)
#>         Estimate         SE         LL        UL exp(Estimate)  exp(LL)
#> Average    0.192 0.04823578 0.09745962 0.2865404      1.211671 1.102367
#> Study 1    0.165 0.06840000 0.03093846 0.2990615      1.179393 1.031422
#> Study 2    0.193 0.09210000 0.01248732 0.3735127      1.212883 1.012566
#> Study 3    0.218 0.08820000 0.04513118 0.3908688      1.243587 1.046165
#>          exp(UL)
#> Average 1.331812
#> Study 1 1.348593
#> Study 2 1.452829
#> Study 3 1.478265

# Should return:
#         Estimate         SE         LL        UL exp(Estimate)
# Average    0.192 0.04823578 0.09745962 0.2865404      1.211671
# Study 1    0.165 0.06840000 0.03093846 0.2990615      1.179393
# Study 2    0.193 0.09210000 0.01248732 0.3735127      1.212883
# Study 3    0.218 0.08820000 0.04513118 0.3908688      1.243587
#          exp(LL)  exp(UL)
# Average 1.102367 1.331812
# Study 1 1.031422 1.348593
# Study 2 1.012566 1.452829
# Study 3 1.046165 1.478265